產(chǎn)品名稱：Anti-Mouse V beta 11 TCR (clone RR8-1) APC, 100 ug 產(chǎn)品規(guī)格：eBioscience 17-5800-82 產(chǎn)品貨號(hào)：100 ug Anti-Mouse V alpha 11 TCR APC Also known as: Valpha11, Va11 Clone: RR8-1 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 17-5800 Cat. No. Size 17-5800-80 25 ug 17-5800-82 100 ug Description: This RR8-1 monoclonal antibody reacts with the mouse T cell receptor (TCR) V alpha 11 chain. Composed of an alpha and beta chain, TCR specificity is typically determined by Va, Ja, Vb, Db, and Jb gene rearrangement. The RR8-1 antibody recognizes the V beta 11 chain on T cells from mouse strains with the b (e.g., C57BL/6, B10) and d (e.g., DBA/1, DBA/2) haplotypes. V alpha 11+ T cells are absent in strains with the a (e.g., BALB/c, C3H) or c (e.g., SJL) haplotypes of the Tcra gene complex. Finally, V alpha 11 is expressed predominantly on CD4+ T cells. The RR8-1 antibody recognizes the V alpha 11.1 and 11.2 alleles, but not 11.3. This antibody has been reported to stimulate V alpha 11+ T cells.
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