產(chǎn)品名稱：APC anti-human CD87 (Clone VIM5), 100 tests 產(chǎn)品規(guī)格：eBioscience 17-3879-42 產(chǎn)品貨號(hào)：100 ug Anti-Human CD87 (UPAR) APC Also known as: UPA Receptor Clone: VIM5 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 17-3879 Cat. No. Size 17-3879-41 25 tests 17-3879-42 100 tests Description: This VIM5 monoclonal antibody reacts with human CD87, a GPI-linked receptor for urokinase plasminogen activator (uPA). By sequestering uPA, CD87 is involved in the conversion of plasminogen to plasmin on the leading edge of migrating cells, a process critical for chemotaxis. CD87 is expressed on the surface of monocytes, dendritic cells, and on activated T and NK cells. Interestingly, in granulocytes, CD87 expressed in the cytoplasm and on the cell surface. Non-hematopoietic cells such as endothelial cells, keratinocytes, and fibroblasts, also express this receptor. Finally, CD87 plays a role in cell adhesion and migration, angiogenesis, and tumor metastasis. This monoclonal antibody has been reported to have neutralization activity.
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