產(chǎn)品名稱：Anti-Human CD142 (clone HTF-1) APC, 100 tests 產(chǎn)品規(guī)格：eBioscience 17-1429-42 產(chǎn)品貨號：100 tests Anti-Human CD142 APC Also known as: Tissue factor Clone: HTF-1 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 17-1429 Cat. No. Size 17-1429-41 25 tests 17-1429-42 100 tests Description: This HTF-1 monoclonal antibody reacts with human CD142, which is also known as Tissue Factor. Expression of this type I transmembrane glycoprotein on endothelial cells, monocytes, macrophages, and platelets can be induced by inflammatory mediators (e.g., LPS, IL-1b, TNFa, PMA, or endotoxin). On the other hand, CD142 is expressed constitutively by some tumor cells (e.g., lung, pancreatic, breast, and colon) and non-immune tissues such as the vasculature, central nervous system, kidney, epithelia, and placenta. Studies have also suggested that CD142 exists as a soluble form that circulates in blood. CD142 initiates blood coagulation by associating with and activating the circulating factors VII and VIIa. The HTF-1 antibody has been reported to exhibit blocking activity.
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