產品名稱：Anti-Human Oncostatin M Receptor APC (AN-V2) 100 tests 產品規(guī)格：eBioscience 17-1303-42 產品貨號：100 tests Anti-Human Oncostatin M Receptor APC Also known as: OSMR Clone: AN-V2 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 17-1303 Cat. No. Size 17-1303-41 25 tests 17-1303-42 100 tests Description: This monoclonal AN-V2 antibody reacts with the human oncostatin M (OSM) receptor. OSM, which belongs to the interleukin-6 cytokine family, is produced by T cells, activated monocytes, and dendritic cells. In humans, OSM can bind two unique receptor complexes. The type I OSM receptor is composed of the LIFR associated with gp130, and recognizes both LIF and OSM. The type II OSM receptor, which consists of gp130 and the OSMR subunit, specifically binds the cytokine, leading to activation of the JAK/STAT signaling pathway. Reports have also indicated a soluble form of the OSM receptor, which this antibody also recognizes. The OSM receptor is expressed in the bone marrow, endothelium, liver, lung, and numerous tumor cell lines. The AN-V2 monoclonal antibody recognizes the type II (beta) OSM receptor.
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