產(chǎn)品名稱:Anti-Human CD103 (Integrin alpha E) (clone Ber-ACT8) APC, 100 tests 產(chǎn)品規(guī)格:eBioscience 17-1037-42 產(chǎn)品貨號(hào):100 tests Anti-Human CD103 (Integrin alpha E) APC Also known as: Integrin aE, ITGAE Clone: Ber-ACT8 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 17-1037 Cat. No. Size 17-1037-41 25 tests 17-1037-42 100 tests Description: The Ber-ACT8 monoclonal antibody reacts with human CD103, the alphaE integrin. CD103 non-covalently associates with integrin beta7. CD103 is expressed mainly on intraepithelial lymphocytes and a small subset of peripheral lymphocytes. CD103 is also expressed by hairy cell leukemia (HCL) and by some chronic B cell lymphocytic leukemias. \I{In vitro\I} stimulation of human T cells with mitogens induces upregulation of CD103. Epithelial cell antigen (E-cadherin) binds to CD103 and mediates homing of lymphocytes to the intestinal epithelium. Cross-blocking studies suggest that antibody clones B-Ly7 and Ber-ACT8 see different epitopes.
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