產品名稱：APC Mouse CD47 (clone miap301), 100 ug 產品貨號：eBioscience 17-0471-82 產品規(guī)格：100 ug Anti-Mouse CD47 APC Also known as: Integrin associated protein, IAP, neurophilin ITPG Clone: miap301 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 17-0471 Cat. No. Size 17-0471-80 25 ug 17-0471-82 100 ug Description: The monoclonal antibody miap301 reacts to CD47 also known as integrin-associated protein (IAP), and neurophilin. CD47 is a glycosylated five transmembrane protein with a small cytoplasmic domain. CD47 is involved in adhesion through interactions with SIRP (signal regulator protein) and is non-covalently associated with ß3 integrins CD51/CD61, CD41/CD61. It is also known to be the receptor for thrombospondin. T cell expression of CD47 can mediate activation or apoptosis (in the presence of high levels of thrombospondin). Expression is found in the majority of hematopoietic cells including T and B cells, monocytes, platelets and erythrocytes (as part of the Rh complex). Expression is also found in non-hematopoietic cells. No crossreactivity is seen against human CD47.
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