產(chǎn)品名稱：Anti-Mouse CD36 APC (No.72-1) 100 ug 產(chǎn)品貨號(hào)：eBioscience 17-0361-82 產(chǎn)品規(guī)格：100 ug Anti-Mouse CD36 APC Also known as: GR4, GP3b, GP IIIb, Thrombospondin Receptor Clone: No.72-1 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 17-0361 Cat. No. Size 17-0361-80 25 ug 17-0361-82 100 ug Description: The No. 72-1 monoclonal antibody reacts with mouse CD36, which is a 88 kDa member of the class B scavenger receptor family. Murine CD36 was discovered using an expression cloning strategy to identify macrophage receptors that recognized oxidized low-density lipoprotein (oxLDL), but not acetylated low-density lipoprotein (LDL). CD36 is a platelet-membrane glycoprotein, but is also expressed on monocytes/macrophages, granulocytes, B lymphocytes, microvascular endothelial cells, adipocytes, skeletal muscle and dendritic cells. The role of CD36 as a scavenger receptor was confirmed by the CD36-deficient mouse, which was defective in the binding and uptake of oxLDL by peritoneal macrophages. In addition to binding oxLDL, CD36 binds other ligands including TSP-1, anionic phospholipids, apoptotic cells, collagen, Plasmodium falciparum-infected erythrocytes and long-chain fatty acids. Testing also shows staining on some B cells in the bone marrow in addition to the myeloid cells.
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