產品名稱：APC Human CD3 (clone OKT3), 100 tests 產品貨號：eBioscience 17-0037-42 產品規(guī)格：100 tests Anti-Human CD3 APC Also known as: Leu-4, T3 Clone: OKT3 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 17-0037 Cat. No. Size 17-0037-41 25 tests 17-0037-42 100 tests Description: The OKT3 monoclonal antibody reacts with an epitope on the epsilon-subunit within the human CD3 complex. The OKT3 antibody has been reported to have potent immunosuppressive properties in vivo and has been proven effective in the treatment of renal, heart and liver allograft rejection. The CD3 subunits, gamma, delta, and epsilon chains, are required for proper assembly, trafficking and surface expression of the TCR complex. CD3 is expressed by thymocytes in a developmentally regulated manner and by all mature T cells. Crosslinking of TCR initiates an intracellular biochemical pathway resulting in cellular activation and proliferation.
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