產(chǎn)品名稱：Functional Grade Purified anti-human podoplanin 500 ug 產(chǎn)品貨號：eBioscience 16-9381-85 產(chǎn)品規(guī)格：500 ug Anti-Human Podoplanin Functional Grade Purified Also known as: PDPN Clone: NZ-1.3 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 16-9381 Cat. No. Size 16-9381-81 50 ug 16-9381-85 500 ug Description: Podoplanin is a 40-kDa type I transmembrane sialomucin-like glycoprotein involved in platelet aggregation and cancer metastasis. This protein is expressed on lymphatic endothelial cells and follicular dendritic cells, as well as on many human cancers, including squamous cell carcinoma, glioblastoma, seminoma, and mesothelioma. Podoplanin expression has been demonstrated to be regulated by the Fos protein of the Activating Protein-1 (AP-1) transcription factor complex. Much of its functionality arises via interaction with its endogenous receptor, C-type lectin-like receptor-2 (CLEC-2). This antibody has been reported to block the interaction between Podoplanin and CLEC-2.
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