產(chǎn)品名稱：Functional grade Mouse/human IL-22 (clone IL22JOP), 500 ug 產(chǎn)品貨號：eBioscience 16-7222-85 產(chǎn)品規(guī)格：500 ug Anti-Human/Mouse IL-22 Functional Grade Purified Also known as: Interleukin-22, IL22 Clone: IL22JOP RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 16-7222 Cat. No. Size 16-7222-82 100 ug 16-7222-85 500 ug Description: The monoclonal antibody IL22JOP reacts with and inhibits the bioactivity of human and mouse IL-22. IL-22 is a 20 kDa member of the IL-10 cytokine family that is secreted primarily by Th17 cells, NK cells, and other T cells. Compared to IL-6 or TGF beta, IL-23 can induce greater levels of IL-22 in in vitro-differentiated Th17 cells. This observation suggests that IL-22 may be secreted by more fully differentiated Th17 cells in vivo. Recently, it was demonstrated that IL-22 could protect hosts from bacterial infection of the lungs and gut. Moreover, it has been reported that anti-CD3/CD28-induced production of IL-22 by PBMCs was elevated significantly in asthma patients compared to control patients. Flow cytometric analysis also showed that the frequencies of IL-17+IL-22+ CD4 T cells were increased in PBMCs from patients with ankylosing spondylitis and rheumatoid arthritis.
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