產(chǎn)品名稱：anti-mouse RAE-1gamma FG Purified CX1 500 ug 產(chǎn)品貨號：eBioscience 16-5881-85 產(chǎn)品規(guī)格：500 ug Anti-Mouse RAE1 gamma Functional Grade Purified Also known as: RAE1gamma, RAE1-g, RAE-1-g Clone: CX1 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 16-5881 Cat. No. Size 16-5881-81 50 ug 16-5881-82 100 ug 16-5881-85 500 ug Description: The CX1 monoclonal antibody reacts with the mouse retinoic acid early inducible gamma (RAE-1γ) and weakly cross-reacts with the RAE-1α and β, but not with δ and ε. These 5 members of the RAE-1 family, along with another protein encoded by the minor histocompatibility gene complex called H60 have been identified as ligands for the mouse NKG2D molecule. These ligands are normally absent from ***** tissue, however the presence of retinoic acid or certain disease conditions (such as tumors) can induce up-regulation of this protein at the cell surface. RAE-1α, -β, and -γ and H60 are expressed in BALB/c mice, but not in C57BL/6, whereas RAE-1δ, and -ε are expressed in C57BL/6 mice. It is reported that in NOD mice, both NKG2D and its ligand RAE-1 are expressed on the same NK cells, resulting in self-modulation of NKG2D expression and function.
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