產(chǎn)品名稱:Functional Grade Human TCR Vbeta 5.1 (clone LC4), 100 ug 產(chǎn)品貨號:eBioscience 16-5832-82 產(chǎn)品規(guī)格:100 ug Anti-Human V beta 5.1 TCR Functional Grade Purified Also known as: Vbeta 5.1, Vbeta5.1, Vb 5.1, Vb5.1 Clone: LC4 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 16-5832 Cat. No. Size 16-5832-80 25 ug 16-5832-82 100 ug Description: This LC4 monoclonal antibody recognizes the human T cell receptor (TCR) Vβ5.1 allele. Composed of an α and β chain, TCR specificity is typically determined by Vaα, Jα, Vβ, Dβ, and Jβ gene rearrangement. Vβ expression in humans has been examined in studies on the effects of superantigens, inflammation, autoimmune disease, and HIV infection. More recently, assessment of TCR Vβ expression has been used to phenotype T cell clonality in CD3+/TCRαβ+ large granular lymphocyte leukemias. A member of the Ig superfamily, this receptor is expressed on a subset of peripheral blood T cells. This monoclonal antibody has been reported to induce apoptosis and calcium flux.
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