產(chǎn)品名稱：anti-mouse FR4 FG Purified eBioTH6 500 ug 產(chǎn)品貨號：eBioscience 16-5446-85 產(chǎn)品規(guī)格：500 ug Anti-Mouse FR4 Functional Grade Purified Also known as: Folate receptor 4, FOLR4 FRdelta, FRd Clone: eBioTH6 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 16-5446 Cat. No. Size 16-5446-82 100 ug 16-5446-85 500 ug Description: The monoclonal antibody eBioTh6 recognizes FR4, also known as FR δ and FBP3 (folate binding protein3). FR4 is a heavily glycosylated 35 kD receptor for folic acid and the physiologic circulating form of the vitamin, N5-methyltetrahydrofolate. Natural T regs have high levels of FR4 and together with CD25 can be used to distinguish natural Tregs, effector T cells, memory-like T cells and naïve T cells. In vivo studies with eBioTH6 show a decrease in the number of CD4+CD25+ cells and an enhanced tumor response leading to the elimination of advanced stages of tumors. Based on co-staining studies, the epitopes recognized by eBioTH6 and eBio12A5 (cat 51-5445) are different thereby allowing functional studies with TH6 to be evaluated with eBio12A5.
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