產(chǎn)品名稱：anti-mouse CD73 FG Purified eBioTY/11.8 (TY/11.8) 100 ug 產(chǎn)品貨號：eBioscience 16-0731-82 產(chǎn)品規(guī)格：100 ug Anti-Mouse CD73 Functional Grade Purified Also known as: Ecto-5'-nucleotidase, NT5E Clone: eBioTY/11.8 (TY/11.8) RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 16-0731 Cat. No. Size 16-0731-80 25 ug 16-0731-82 100 ug Description: eBioTY/11.8 recognizes the with CD73 a 69-kDa GPI-anchored cell-surface protein with ecto-5'-nucleotidase activity. Expression on myeloid cells (CD11b) is restricted to the bone marrow. In human CD73 can be induced to secrete a soluble form with IL-2 suggesting a role in mediating activation signals. Differences between human and mouse CD73 have been reported. BALB/c mice have more CD4+CD73+ than CD8+CD73+ while the reciprocal is documented in humans. CD73 is expressed on a subset of lymphocytes and increases during lymphocyte maturation. Recently it has been found that memory CD4 T cells express and are similar to the uncommitted primed precursor helper cells (Thpp) that can differentiate into Th1 or Th2 cells. Furthermore CD73 has been found on regulatory T cells.
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