產(chǎn)品名稱：Functional Grade Mouse CD47 (clone MIAP301), 500 ug 產(chǎn)品貨號：eBioscience 16-0471-85 產(chǎn)品規(guī)格：500 ug Anti-Mouse CD47 Functional Grade Purified Also known as: Integrin associated protein, IAP Clone: miap301 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 16-0471 Cat. No. Size 16-0471-81 50 ug 16-0471-85 500 ug Description: The monoclonal antibody miap301 reacts to CD47 also known as integrin-associated protein (IAP), and neurophilin. CD47 is a glycosylated five transmembrane protein with a small cytoplasmic domain. CD47 is involved in adhesion through interactions with SIRP (signal regulator protein) and is non-covalently associated with ß3 integrins CD51/CD61, CD41/CD61. It is also known to be the receptor for thrombospondin. T cell expression of CD47 can mediate activation or apoptosis (in the presence of high levels of thrombospondin). Expression is found in the majority of hematopoietic cells including T and B cells, monocytes, platelets and erythrocytes (as part of the Rh complex). Expression is also found in non-hematopoietic cells. No crossreactivity is seen against human CD47.
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