產(chǎn)品名稱：anti-mouse CD39 (Entpd1, NTPDase1) FG Purified 24DMS1 200 ug 產(chǎn)品貨號(hào)：eBioscience 16-0391-83 產(chǎn)品規(guī)格：200 ug Anti-Mouse CD39 Functional Grade Purified Also known as: Ectonucleoside Triphosphate Diphosphohydrolase 1, Entpd1 Clone: 24DMS1 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 16-0391 Cat. No. Size 16-0391-83 200 ug Description: The 24DMS1 monoclonal antibody reacts with mouse CD39, also known as NTPDaseI. E-NTPDases are enzymes that convert nucleoside tri- and diphosphates (NTDPs) into nucleoside monophosphate (NMP), thereby removing toxic extracellular ATP and ADP. CD39 is the dominant member of this family in the immune system and is involved in suppression of inflammation and control of platelet activation. CD39 can impact expression of CD73, another E-NTPase. Together, these molecules influence inflammation responses. CD39 is expressed on B cells, Langerhans cells and most monocytes. In addition, CD39 is found on a subset of CD4+ T cells that are mostly CD25+FoxP3+ T reg cells. T reg cells from CD39-null mice showed impaired suppressive properties in vitro and in vivo.
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