產(chǎn)品名稱(chēng)：anti-mouse/human CD27 FG Purified LG.3A10 500 ug 產(chǎn)品貨號(hào)：eBioscience 16-0272-85 產(chǎn)品規(guī)格：500 ug Anti-Human/Mouse CD27 Functional Grade Purified Also known as: TNFRSF7 Clone: LG.3A10 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 16-0272 Cat. No. Size 16-0272-81 50 ug 16-0272-85 500 ug Description: The LG.3A10 monoclonal antibody reacts with mouse CD27, a lymphocyte-specific member of the TNFR superfamily. CD27 is expressed by virtually all mature T cells and by a subpopulation of B cells, mainly memory B cells. In mouse, CD27 has been found on nearly all thymocytes excluding a population of CD46-CD8- precursors. CD27 binds to CD70 and, through this interaction, plays an important role in T cell-B cell interaction. It has been reported that triggering CD27 plays an important role in the maturation of CD4+ and CD8+ effector cells. LG.8F10 cross-reacts with human and rat CD27. When the monoclonal antibody LG.3A10 is crosslinked on purified T cells, proliferation is increased. In the absence of crosslinking, the antibody inhibits CD27-CD70 interaction.
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