產品名稱：anti-mouse CD14 FG Purified Sa2-8 500 ug 產品貨號：eBioscience 16-0141-85 產品規(guī)格：500 ug Anti-Mouse CD14 Functional Grade Purified Also known as: LPS-R, Mo2 Clone: Sa2-8 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 16-0141 Cat. No. Size 16-0141-81 50 ug 16-0141-82 100 ug 16-0141-85 500 ug Description: The Sa2-8 monoclonal antibody reacts with mouse CD14, a 53-55 kDa GPI-linked glycoprotein. CD14 is a receptor for the complexes of LPS and LBP (LPS-Binding Protein) and is shown to associate with Toll-Like Receptor 4 (TLR4) and participate in the signaling and cellular response to bacterial LPS. In mouse, CD14 is expressed on the surface of macrophages and under certain conditions is also found in the serum in a secreted form. Sa2-8 has weak antagonistic activity (in NF-kappaB activation or TNF alpha production with LPS stimulation).
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