產品名稱：anti-mouse CD117 PE-Cy5 ACK2 200 ug 產品貨號：eBioscience 15-1172-83 產品規(guī)格：200 ug Anti-Mouse CD117 (c-Kit) PE-Cy5 (To be Discontinued; alternative clone Cat. No. 15-1171) Also known as: cKit, Steel Factor Receptor Clone: ACK2 RUO: For Research Use Only. Not for use in diagnostic procedures. Attention: Alternative clone 2B8 is available. See Cat. No. 15-1171. SKU# 15-1172 Cat. No. Size 15-1172-81 50 ug 15-1172-82 100 ug 15-1172-83 200 ug Description: The ACK2 monoclonal antibody reacts with mouse CD117, also known as c-Kit receptor, Steel factor receptor and stem cell factor receptor. A member of the tyrosine kinase receptor family, this 145 kDa molecule is expressed by a majority of hematopoietic progenitor cells characterized in the mouse bone marrow as a small subset of cells positive for Sca-1 and Thy1 (Thy1lo) and negative for lineage markers. The interaction of the mouse c-kit receptor and steel factor promotes the proliferation and differentiation of hematopoietic progenitor cells. CD117 is also expressed by mast cells and plays a role in signaling and activation of these cells. ACK2 has been reported to be a blocking antibody.
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