產(chǎn)品名稱：Affinity Purified anti-mouse/human FOXJ1 (HFH-4, HFH4) 100 ug 產(chǎn)品貨號(hào)：eBioscience 14-9965-82 產(chǎn)品規(guī)格：100 ug Anti-Human/Mouse FOXJ1 Purified Also known as: HFH-4, HFH4, Fox J1 Clone: 2A5 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 14-9965 Cat. No. Size 14-9965-80 25 ug 14-9965-82 100 ug Description: This 2A5 monoclonal antibody reacts with Foxj1, a 50-kDa member of the Forkhead-box (FOX) family of winged-helix transcription factors. Expression of Foxj1 is high in ciliated epithelial cells and low in naïve T and B cells, where cellular activation results in downregulation of the factor. Foxj1 modulates germinal center formation and Th1 activation by repressing NFκB through IκBβ induction. As such, this transcription factor has been suggested to antagonize autoimmune reactions such as systemic lupus erythematosus and rheumatoid arthritis. In addition, Foxj1 has been linked to the formation of motile cilia in epithelial cells.
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