產(chǎn)品名稱：Purified anti-human IRF-3 (interferon regulatory factor 3) 100 ug 產(chǎn)品貨號：eBioscience 14-9947-82 產(chǎn)品規(guī)格：100 ug Anti-Human IRF3 Purified Also known as: IRF 3, interferon regulatory factor-3 Clone: SL-12 (SL12) RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 14-9947 Cat. No. Size 14-9947-80 25 ug 14-9947-82 100 ug Description: This SL-12 monoclonal antibody reacts with human Interferon Regulatory Factor (IRF)-3. IRF-3 is a 427 amino acid constitutively expressed member of the IRF transcription factor family that plays a critical role in the induction of type I interferons. Inactive IRF-3 continuously transits between the cytoplasm and nucleus. Virus or dsRNA induces the C-terminal phosphorylation of IRF-3 by IKKε and TBK-1. This phosphorylation results in retention of IRF-3 in the nucleus and subsequent transcription of IFN-ß, several interferon stimulated genes (ISGs), and other antiviral response genes.
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