產品名稱：anti-human CD200 Purified OX104 100 ug 產品貨號：eBioscience 14-9200-82 產品規(guī)格：100 ug Anti-Human CD200 Purified Also known as: OX2, OX-2 Clone: OX104 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 14-9200 Cat. No. Size 14-9200-80 25 ug 14-9200-82 100 ug Description: The monoclonal antibody OX104 recognizes human CD200 also known as OX2. CD200 is a member of the Ig superfamily with 2 Ig domains, a transmembrane and cytoplasmic domain. CD200 is expressed on resting and activated B cells, a subset of resting and activated T cells, keratinocytes, peripheral and central nerve cells, follicular dendritic cells and ovarian cells. The interaction with CD200R results in macrophage activation (IL-6 production), inhibition of mast cell degranulation along with reduced TNFα and IL-13 secretion and overall attenuation of the activation status of lymphocytes. A role has also been suggested in maternal tolerance as expression of CD200 is also present on the trophoblast.
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