產(chǎn)品名稱:anti-mouse Toll-like receptor 1 (CD281) Purified eBioLD5 25 ug 產(chǎn)品貨號:eBioscience 14-9012-80 產(chǎn)品規(guī)格:100 ug Anti-Mouse CD281 (TLR1) Purified Also known as: TLR-1, toll-like receptor 1 Clone: eBioLD5 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 14-9012 Cat. No. Size 14-9012-80 25 ug Description: The eBioLD5 monoclonal antibody reacts with mouse Toll-like receptor 1 (TLR1, CD281). TLR1 is an approximately 98 kDa protein belonging to the Toll-like receptor family, and is closely-related to mouse TLR6 in both structure and function. Through the formation of a complex with TLR2, TLR1 is able to bind bacterially-derived triacyl lipopeptides, as well as soluble factors released from Neisseria meningitidis. TLR1 is expressed by macrophages and macrophages in TLR1-deficient mice display impaired production of inflammatory cytokines upon stimulation with triacyl lipopeptides and lipoproteins from mycobacteria.
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