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產(chǎn)品名稱:anti-mouse Toll-like receptor 1 (CD281) Purified eBioTR23 (TR23) 25 ug
產(chǎn)品貨號:eBioscience 14-9011-80
產(chǎn)品規(guī)格:100 ug
Anti-Mouse CD281 (TLR1) Purified
Also known as: TLR-1, toll-like receptor 1
Clone: eBioTR23 (TR23)
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 14-9011
Cat. No. Size
14-9011-80 25 ug
Description: The eBioTR23 monoclonal antibody reacts with mouse Toll-like receptor 1 (TLR1, CD281). TLR1 is an approximately 98 kDa protein belonging to the Toll-like receptor family, and is closely-related to mouse TLR6 in both structure and function. Through the formation of a complex with TLR2, TLR1 is able to bind bacterially-derived triacyl lipopeptides, as well as soluble factors released from Neisseria meningitidis. TLR1 is expressed by macrophages and macrophages in TLR1-deficient mice display impaired production of inflammatory cytokines upon stimulation with triacyl lipopeptides and lipoproteins from mycobacteria.