產(chǎn)品名稱：Affinity purified Anti-acidic cytokeratin (clone AE1), 100 ug 產(chǎn)品貨號：eBioscience 14-9001-82 產(chǎn)品規(guī)格：100 ug Anti-Acidic Cytokeratin Purified Also known as: keratin Clone: AE1 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 14-9001 Cat. No. Size 14-9001-80 25 ug 14-9001-82 100 ug Description: The monoclonal antibody AE1 recognizes many members of the acidic (Type I) family of cytokeratins. Cytokeratins are intermediate filament proteins comprising one component of the cytoskeleton. There are two large families of cytokeratins, acidic and basic, but all contain the same basic domains (i.e. an α-helical core with an N- and C-terminal domain). The proteins are expressed in epithelial cells, but are developmentally regulated. Many tumors also express these cytokeratins, and their expression can help identify the origin of a neoplasm. The AE1 monoclonal antibody recognizes 56.5, 50, 50’, 48, and 40 kDa proteins (also known as CK10, 14, 15, 16 and 19) in mouse, human, rat, primate (cynomolgus and rhesus), dog, cat, rabbit and chicken.
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