產(chǎn)品名稱：PDGF-BB Recombinant Protein 25 ug 產(chǎn)品貨號(hào)：eBioscience 14-8003-80 產(chǎn)品規(guī)格：25 ug Mouse PDGF-BB Recombinant Protein Also known as: Platelet-Derived Growth Factor BB RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 14-8003 Cat. No. Size 14-8003-62 5 ug 14-8003-80 25 ug Description: PDGF-BB is a member of the platelet-derived growth factor family, a group of proteins that is released by platelets upon activation. The PDGF proteins are dimers of two of four peptide chains designated A, B, C, and D. PDGF-BB is formed by two B-chains, while PDGF-AB is one B chain and one A-chain forming the only heterodimer in the family. PDGF-BB is unique among the family in that it can bind to and activate all three forms of the PDGF receptor. It induces the proliferation, migration, and survival of fibroblasts, endothelial cells, epithelial cells, and smooth muscle cells. PDGF-BB plays an important role in angiogenesis and smooth muscle development during embryogenesis, and is important for wound healing and regeneration in *****s. High levels of PDGF-BB are often detected in malignant tumors, and it is believed to facilitate tumor metastasis and angiogenesis.
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