產(chǎn)品名稱：anti-mouse/rat CCL3 (MIP-1 alpha) Purified Polyclonal 500 ug 產(chǎn)品貨號：eBioscience 14-7995-85 產(chǎn)品規(guī)格：500 ug Anti-Mouse/Rat CCL3 (MIP-1 alpha) Purified Also known as: MIP1A, MIP1 alpha, MIP1a, CC chemokine ligand 3, chemokine (C-C motif) ligand 3, SCYA3 Clone: Polyclonal RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 14-7995 Cat. No. Size 14-7995-81 50 ug 14-7995-85 500 ug Description: The CCL3 polyclonal antibody reacts with both mouse and rat CCL3, also known as MIP-1α (macrophage inflammatory protein-1 alpha). The antibody was generated using E. coli-expressed amino acids 1-69 of mature rat CCL3 as an immunogen. CCL3 is a 69-amino acid CC chemokine with a molecular weight of 7.9 kDa. CCL3 induces migration of monocytes/macropages, B lymphocytes, activated CD8+ T cells, natural killer (NK) cells, and eosinophils. CCL3 also stimulates basophils to release histamine, induces ICAM-1 expression, mast cell degranulation, and production of TNF-α, IL-1 and IL-6. In addition to its proinflammatory activities, CCL3 inhibits the proliferation of hematopoietic stem cells in vitro and in vivo. Cross-reactivity to CCL3 of other species has not been determined.
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