產(chǎn)品名稱：anti-human c-Myc p67 Purified 9E10 100 ug 產(chǎn)品貨號：eBioscience 14-6784-82 產(chǎn)品規(guī)格：100 ug Anti-Human c-Myc p67 Purified Also known as: Myc proto-oncogene protein Clone: 9E10 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 14-6784 Cat. No. Size 14-6784-80 25 ug 14-6784-82 100 ug Description: The 9E10 antibody reacts with human c-Myc p67; the antibody was raised against a synthetic peptide corresponding to amino acids 408-439 within the carboxy terminal domain of human c-Myc. This antibody can be used to detect myc-tagged protein. The transcription factor c-Myc is a proto-oncogene that is at the focal point in cell cycle regulation, metabolism, apoptosis, differentiation, cell adhesion, and tumorigenesis (1-3). In normal cells the expression of c-Myc is tightly regulated but in human cancers c-Myc is frequently deregulated (2&3).c-Myc also plays a pivotal role in apoptosis, most notably its connections to the CD95/Fas death receptor pathway (1&4). These different biological responses to c-Myc are most likely the result of different overlapping subsets of c-Myc target genes (1).
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