產(chǎn)品名稱：anti-mouse/human/rat Cyclin E Purified Polyclonal 50 ug 產(chǎn)品貨號：eBioscience 14-6714-81 產(chǎn)品規(guī)格：50 ug Anti-Cyclin E Purified Clone: Polyclonal RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 14-6714 Cat. No. Size 14-6714-63 10 ug 14-6714-81 50 ug Description: The polyclonal antibody reacts with mouse, human, and rat cyclin E; the antibody was raised against a peptide mapping to the carboxy terminus of rat cyclin E. During each cell cycle cyclins undergo periodic accumulation and destruction. As key regulators of the cell cycle the cyclins control important transitions by activating Cdks (1,2). Early in the G1 phase of the cell cycle cyclin D1 induction is followed by cyclin E induction (3,4). This sequential progression is marked early on in G1by the activation of Cdk4 and in mid to late G1 by the activation of Cdk2 and the hyperphosphorylation of pRB (3,5). The final transition into S phase is thought to be dependent on the increased expression and association of cyclin E and Cdk2 (5,6).
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