產(chǎn)品名稱:Anti-AIM2 Purified (pAb) 100 ul 產(chǎn)品貨號:eBioscience 14-6008-93 產(chǎn)品規(guī)格:500 ug Anti-AIM2 Purified Also known as: Antigen isolated from Immunoselected Melanoma 2, AIM-2 Clone: Polyclonal RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 14-6008 Cat. No. Size 14-6008-93 100 uL Description: This polyclonal antibody reacts with human, mouse, and rat AIM2 (also known as Antigen isolated from Immunoselected Melanoma 2). A member of the HIN-2000 family, this 40-kDa cytoplasmic protein is expressed in the spleen, small intestine, peripheral blood lymphocytes, and testis. Moreover, AIM2 is expressed in tumors of the neuroectodermis, breast, ovary, and colon. As a component of the inflammosome, AIM2 detects double-stranded viral and bacterial DNA present in the cytosol and initiates Caspase1 activation. Expression of AIM2 can be induced by interferons.
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