產(chǎn)品名稱:anti-mouse VEGFR3 Purified AFL4 500 ug 產(chǎn)品貨號:eBioscience 14-5988-85 產(chǎn)品規(guī)格:500 ug Anti-Mouse VEGF Receptor 3 Purified Also known as: VEGFR3, VEGF R3, VEGF receptor 3, Flt-4, Flt4, vascular endothelial growth factor receptor 3 Clone: AFL4 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 14-5988 Cat. No. Size 14-5988-81 50 ug 14-5988-82 100 ug 14-5988-85 500 ug Description: The AFL4 monoclonal antibody reacts with the mouse VEGF receptor-3, also known as Flt-4. This 195 kDa molecule was identified as an endothelial-specific member of the receptor tyrosine kinase (RTK) family. During early embryogenesis all endothelial cells express VEGFR-3, while in the ***** tissues, VEGFR-3 expression disappears from the vascular endothelial cells and is observed only on the lymphatic endothelium. However, VEGFR-3 expression is induced in the ***** tissue upon tumor implementation suggesting an important role for this receptor in the tumor angiogenesis. VEGF-C and VEGF-D bind to and activate VEGFR-3. AFL4 is an antagonist mAb.
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