產(chǎn)品名稱：anti-mouse Ly49H Purified 3D10 100 ug 產(chǎn)品貨號：eBioscience 14-5886-82 產(chǎn)品規(guī)格：100 ug Anti-Mouse Ly-49H Purified Also known as: Ly49H, Ly49 Clone: 3D10 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 14-5886 Cat. No. Size 14-5886-81 50 ug 14-5886-82 100 ug Description: The monoclonal antibody 3D10 recognizes Ly-49H, a member of the C-type lectin Ly-49 multigene family of receptors found on natural killer cells. Ly-49H, like Ly-49D, lacks the characteristic ITIM (immunoreceptor tyrosine-based inhibitory motif) and contains an arginine in the transmembrane domain implying these molecules act as activation receptors. Ly-49H is expressed in a subset of NK cells but not NKT (NK1.1CD3+) cells. Natural killer cells can express several Ly-49 proteins. It has been shown that there is preferential staining of Ly-49H with Ly-49D (cat 12-5783). Expression has been confirmed on C57BL/6 and NWNA but not Balb/c or DBA/2 mice. Other mice strains have not been tested. No crossreactivity to Ly-49A, C, D or G2 has been observed. Addition of monoclonal antibody 3D10 to cell cultures induces lysis of target cells.
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