產(chǎn)品名稱：anti-mouse Nod2 Purified 26mNOD2 100 ug 產(chǎn)品貨號：eBioscience 14-5858-82 產(chǎn)品規(guī)格：100 ug Anti-Mouse NOD2 Purified Also known as: NOD-2, CARD15 Clone: 26mNOD2 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 14-5858 Cat. No. Size 14-5858-81 50 ug 14-5858-82 100 ug Description: The monoclonal antibody 26mNOD2 reacts with mouse NOD2. NOD2, also referred to as caspase recruitment domain-containing protein 15 (CARD 15), is a cytosolic protein of approximately 115kDa. NOD2 contains a central NOD (nucleotide oligomerization domain) that is flanked by a C-terminal leucine-rich repeat (LRR) domain and an N-terminal CARD domain. The LRR confers recognition of microbial components such as muramyl dipeptide and the CARD domain confers the ability to interact with RIP2 via homotypic interaction with the RIP2 CARD. This interaction leads to downstream activation of NF-κB. The antibody 26mNOD2 has been shown to recognize protein from transgenic and transfected cells. Expression on endogenous tissue is still under evaluation.
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