產(chǎn)品名稱：Purified Mouse/human Oct-2 (clone 9A2), 100 ug 產(chǎn)品貨號(hào)：eBioscience 14-5840-82 產(chǎn)品規(guī)格：100 ug Anti-Human/Mouse OCT2 Purified Also known as: Oct-2, octamer-binding transcription factor, POU2F2 Clone: 9A2 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 14-5840 Cat. No. Size 14-5840-80 25 ug 14-5840-82 100 ug Description: This monoclonal 9A2 antibody recognizes human and mouse Oct2, a transcription factor that binds conserved octamer DNA motifs within immunoglobulin promoters. The structure of the Oct2 protein consists of an amino terminal glutamine-rich domain, a central POU homeodomain and a carboxy terminal transactivation domain. Predominantly expressed in the nucleus of B cells, Oct2 has also been found in activated T cells and a subset of myeloid cells. Based on knock-out studies, expression is not required for B cell commitment but is required for maturation. In addition to developmental expression, Oct2 has been associated with neoplasm and maybe a useful tool for characterization of DLBCL and classical Hodgkin’s disease.
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