產(chǎn)品名稱：Anti-Human/Non-Human Primate CD8b (clone SIDI8BEE) Purified, 100 ug 產(chǎn)品貨號：eBioscience 14-5273-82 產(chǎn)品規(guī)格：100 ug Anti-Human/Non-Human Primate CD8b Purified Clone: SIDI8BEE RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 14-5273 Cat. No. Size 14-5273-80 25 ug 14-5273-82 100 ug Description: The SIDI8BEE monoclonal antibody reacts with human and rhesus macaque CD8 beta. The CD8b chain associates with the CD8a chain to form the CD8ab heterodimer expressed on the surface of a majority of thymocytes, and on peripheral cytotoxic alphabeta TCR T cells. The CD8 receptor complex binds to MHC class I and plays a role in T cell development and activation of mature T cells. Long been thought to exist either as a heterodimer of the alpha and beta chain or as a homodimer of alpha chains, beta chains have now been shown to homodimerize as well. SIDI8BEE can detect the CD8 beta chain in both the CD8ab heterodimer and the CD8bb homodimer. SIDI8BEE is cross-reactive to human and rhesus macaque CD8b. Other non-human primate species have not been tested.
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