產(chǎn)品名稱：Purified anti-mouse H2M3 (Clone mAb 130), 100 ug 產(chǎn)品貨號：eBioscience 14-5230-82 產(chǎn)品規(guī)格：100 ug Anti-Mouse MHC Class Ib (H2-M3) Purified Also known as: MHC Ib, H2M3 Clone: mAb 130 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 14-5230 Cat. No. Size 14-5230-80 25 ug 14-5230-82 100 ug Description: This mAb 130 monoclonal antibody reacts with mouse MHC class Ib H2-M3. This molecule specifically binds N-formylated peptides, which arise from mitochondrial or bacterial proteins. H2-M3-restricted T cells are mainly cytotoxic CD8+ T cells. H2-M3 associates with β2-microglobulin. Finally, H2-M3 is expressed on cells in the spleen, Peyer’s patches, and lymph nodes, but not in the thymus. More specifically, cell surface expression of H2-M3 is low on B cells. However, H2-M3 can be induced by incubation with N-formylated peptide on T and B cells, macrophages, and dendritic cells.
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