產(chǎn)品名稱:anti-mouse CD199 (CCR9) Purified eBioCW-1.2 (CW-1.2) 500 ug 產(chǎn)品貨號(hào):eBioscience 14-1991-85 產(chǎn)品規(guī)格:500 ug Anti-Mouse CD199 (CCR9) Purified Also known as: C-C chemokine receptor type 9, CCR-9, GPR28, Cmkbr10 Clone: eBioCW-1.2 (CW-1.2) RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 14-1991 Cat. No. Size 14-1991-80 25 ug 14-1991-82 100 ug 14-1991-85 500 ug Description: The eBioCW-1.2 monoclonal antibody reacts with mouse CCR9 (CD199), which is the receptor for thymus-expressed chemokine (TECK). CCR9 is a member of the G protein coupled receptor (GPCR) supergene family, and is involved in trafficking of T cell progenitors within the thymus. CCR9 expression during thymocyte development commences at the double-negative (DN) 3 stage (CD4-CD8-CD25+CD44-), peaks in the double-positive (DP) stage (CD4+CD8+CD25-CD44-), and is down-regulated in commited CD4+ or CD8+ single-positive (SP) thymoyctes. CCR9-deficient mice show a mild impairment in thymoycte development. In the periphery, CCR9 is thought to be expressed on naïve CD8+ T cells, but not on naïve CD4+ T cells.
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