產(chǎn)品名稱:anti-mouse CCR5 (CD195) Purified HM-CCR5 (7A4) 500 ug 產(chǎn)品貨號(hào):eBioscience 14-1951-85 產(chǎn)品規(guī)格:500 ug Anti-Mouse CD195 (CCR5) Purified Also known as: MIP-1 alpha Receptor C-C chemokine receptor type 5, Cmkbr5 Clone: HM-CCR5 (7A4) RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 14-1951 Cat. No. Size 14-1951-81 50 ug 14-1951-82 100 ug 14-1951-85 500 ug Description: CCR5 is the major co-receptor for macrophage-tropic isolates of HIV-1. CCR5, also known as CD195, is a seven transmembrane chemokine receptor capable of binding RANTES, MIP-1 alpha and MIP-1 beta. Knockout mice show a decreased recruitment of macrophages and increased susceptibility to infection. Protein and mRNA has been found in macrophages from thioglycolate-treated and activated T cells. The HM-CCR5(7A4) monoclonal antibody binds the N terminal extracellular domain of mouse CCR5 with no crossreactivity to human CCR5.
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