產(chǎn)品名稱：Purified mouse/human IL-20R2 (clone 20RNTC), 100 ug 產(chǎn)品貨號：eBioscience 14-1206-82 產(chǎn)品規(guī)格：100 ug Anti-Human/Mouse IL-20 Receptor 2 (IL-20Rb) Purified Also known as: Interleukin-20 Receptor Clone: 20RNTC RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 14-1206 Cat. No. Size 14-1206-80 25 ug 14-1206-82 100 ug Description: This 20RNTC monoclonal antibody recognizes mouse and human IL-20R2 (interleukin-20 receptor 2, IL-20Rb) in either of its two heterodimeric complexes formed by pairing with IL-20R1 or IL-22R1. IL-20R2 belongs to the class II cytokine receptor family that shares a characteristic pattern of cysteine, proline and tryptophan residues in the extracellular domain. IL-20R2 paired with IL-20R1 forms a receptor that binds IL-20, IL-19, or IL-24. IL-20R2 paired with IL22R1 forms a receptor that binds IL-20 or IL-24. The IL-20R complex signals primarily via the JAK-STAT pathway. IL-20R2 is found predominantly on cells of epithelial origin such as gut and skin and can be upregulated during inflammation. Immunofluorescent staining of A375 cells reveals a punctate staining pattern at the cell membrane, as well as diffuse, cytoplasmic staining that is likely associated with protein synthesis and transport in the endoplasmic reticulum and golgi.
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