產(chǎn)品名稱:anti-mouse TNFR2p75 (CD120b) Purified TR75-54 500 ug 產(chǎn)品貨號:eBioscience 14-1203-85 產(chǎn)品規(guī)格:500 ug Anti-Mouse CD120b (TNF Receptor II) Purified Also known as: TNFRSF1A, TNFR1p55, TNF RI, TNFRI, TNF receptor superfamily member 1A, TNFR55, TNFR60 Clone: TR75-54 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 14-1203 Cat. No. Size 14-1203-81 50 ug 14-1203-85 500 ug Description: The TR75-54 monoclonal antibody reacts with mouse Tumor Necrosis Factor Receptor II (TNFRII, TNFR-p80, TNFRSF1B, CD120b). TNFRII is expressed in a variety of cell types and strongly expressed on stimulated T and B lymphocytes. TNFRII is the main TNF receptor found on circulating T cells and is the major mediator of autoregulatory apoptosis in CD8+ cells. The soluble TNF receptors are truncated forms of cell surface receptors with neutralizing activity on both TNF-α and TNF-β. It has been suggested that the proinflammatory and immunosuppressive properties of TNF segregate at the level of its receptors and that the pool of TNF bound to soluble receptors could represent a reservoir to control the TNF release.
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