產(chǎn)品名稱：anti-mouse CD106 Purified 429 500 ug 產(chǎn)品貨號：eBioscience 14-1061-85 產(chǎn)品規(guī)格：500 ug Anti-Mouse CD106 (VCAM-1) Purified Also known as: VCAM1 Clone: 429 RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 14-1061 Cat. No. Size 14-1061-81 50 ug 14-1061-82 100 ug 14-1061-85 500 ug Description: The 429 monoclonal antibody reacts with mouse CD106 (Vascular Cell Adhesion Molecule-1, VCAM-1), a 110 kDa transmembrane glycoprotein expressed by myeloid lineage and bone marrow stromal cells. Endothelial cells constitutively express low levels of CD106 and upregulate it upon cytokine stimulation. CD106 binds to integrin α4β1 (VLA-4, CD49d/CD29) and Integrin a4b7 (LPAM-1) and these interactions in the bone marrow and thymus are important for early lymphocyte and myeloid development. Cytokine-mediated upregulation of CD106 on endothelial cells suggests a role for this antigen in the inflammatory response.
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