產(chǎn)品名稱：anti-rat CD106 Purified eBioMR106 (MR106) 500 ug 產(chǎn)品貨號：eBioscience 14-1060-85 產(chǎn)品規(guī)格：500 ug Anti-Rat CD106 (VCAM-1) Purified Also known as: VCAM1 Clone: eBioMR106 (MR106) RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 14-1060 Cat. No. Size 14-1060-82 100 ug 14-1060-81 50 ug 14-1060-85 500 ug Description: The eBioMR106 monoclonal antibody reacts with rat CD106 (Vascular Cell Adhesion Molecule-1, VCAM-1), a 110 kDa transmembrane glycoprotein expressed by myeloid lineage and bone marrow stromal cells. Endothelial cells constitutively express low levels of CD106 and further upregulate VCAM-1 upon cytokine stimulation. CD106 binds to integrin α4β1 (VLA-4, CD49d/CD29) and Integrin α4β7 (LPAM-1) and these interactions in the bone marrow and thymus are important for early lymphocyte and myeloid development. Cytokine-mediated upregulation of CD106 on endothelial cells suggests a role for this antigen in the inflammatory response.
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