產(chǎn)品名稱： anti-rat CD86 Purified 24F 500 ug 產(chǎn)品貨號(hào)：eBioscience 14-0860-85 產(chǎn)品規(guī)格：100 ug Anti-Rat CD86 (B7-2) Purified Also known as: B72 Clone: 24F RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 14-0860 Cat. No. Size 14-0860-81 50 ug 14-0860-82 100 ug 14-0860-85 500 ug Description: The 24F monoclonal antibody reacts with rat CD86, an ~90 kDa surface receptor, also known as B7-2. CD86 and CD80 are members of the B7 family of costimulatory molecules. CD86 is expressed by germinal center B cells and at low levels on macrophages, dendritic cells and non-lymphoid cells in the thymus. Its expression is upregulated on B cells through a variety of surface stimuli including LPS. In addition to CD80 (B7-1), CD86 is a counter-receptor for the T cell surface molecules CD28 and CD152 (CTLA-4). The interaction of CD86 with its ligands plays a critical role in T-B crosstalk, T cell costimulation, autoantibody production and Th2-mediated Ig production. The kinetics of upregulation of CD86 upon stimulation supports its major contribution during the primary phase of an immune response.
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