英文名Hydrocortisone 中文名: 可的索;皮質(zhì)醇;氫化皮質(zhì)酮;氫可的松 ,氫化可的松 說明:類別腎上腺皮質(zhì)**及促腎上腺皮質(zhì)**藥 Sigma H0888 Hydrocortisone cell culture tested Synonym: 11β,17α,21-Trihydroxypregn-4-ene-3,20-dione, 17-Hydroxycorticosterone, 4-Pregnene-11β,17α,21-triol-3,20-dione, Cortisol, Kendall’s compound F, Reichstein’s substance M CAS Number: 50-23-7 Linear Formula: C21H30O5 Molecular Weight: 362.46 Beilstein Registry Number: 1354819 EC Number: 200-020-1 MDL number: MFCD00011654 PubChem Substance ID: 24895415 Description Reconstitution To prepare 50 μg/mL stock solution, add 1.0 mL absolute ethanol to 1.0 mg of product, gently swirl to dissolve, add 19 mL sterile medium. Physical form powder-RT; stock-frozen in working aliquots, avoid repeated freeze/thaw Biochem/physiol Actions Primary glucocorticoid secreted by the adrenal cortex. It has three times the anti-inflammatory potency of corticosterone but much lower Na2+ retention potency. 性質(zhì) assay ≥98% potency 0.004-5 μg/mL mp 211-214 °C(lit.) suitability cell culture tested Gene Information human ... ABCB1(5243), CYP3A4(1576), SERPINA6(866) rat ... Ar(24208), Nr3c1(24413) mouse ... Abcb1a(18671), Abcb1b(18669), Ifng(15978), Nos2(18126)
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