氯霉素
英文名: Chloramphenicol , D(-)-threo-2-Dichloroacetamido-1-(p-nitrophenyl)-1,3-propanediol
性 狀: 針狀或細(xì)長的片狀結(jié)晶。真空時升華。25℃時溶解度：水中2.5mg/ml、丙二醇中150.8mg/ml。易溶于甲醇、乙醇、丁醇、乙酸乙酯、丙酮，微溶于乙醚，不溶于苯、石油醚、植物油。水溶液呈中性。中性或酸性溶液受熱時穩(wěn)定。熔點150.5～151.5℃。比旋光度［α］27D+18.6°(c=4.86,乙醇中)，［α］２５Ｄ-25.5°(乙酸乙酯中)。*大吸收波長278nm(Ｅ１％1cm298)。
用 途:生化研究。組織培養(yǎng)基。醫(yī)藥
Simga相關(guān)產(chǎn)品資料
Sigma C0378 Chloramphenicol
≥98% (TLC)
Synonym:
Chloromycetin®, D-threo-2,2-Dichloro-N-[β-hydroxy-α-(hydroxymethyl)-4-nitrophenethyl]acetamide, D-(−)-threo-2,2-Dichloro-N-[β-hydroxy-α-(hydroxymethyl)-β-(4-nitrophenyl)ethyl]acetamide, D-(−)-threo-2-Dichloroacetamido-1-(4-nitrophenyl)-1,3-propanediol
CAS Number:
56-75-7
Linear Formula:
Cl2CHCONHCH(CH2OH)CH(OH)C6H4NO2
Molecular Weight:
323.13
Beilstein Registry Number:
2225532
EC Number:
200-287-4
MDL number:
MFCD00078159
PubChem Substance ID:
24892250
Biochem/physiol Actions
Mode of Action: Inhibits translation on the 50S ribosomal subunit at the peptidyltransferase step (elongation inhibition). Bacteriostatic. Mode of Resistance: Acetylation by chloramphenicol acetyltransferase (cat gene).
Legal Information
Chloromycetin is a registered trademark of Parke-Davis & Co.
assay
mp
148-150 °C(lit.)
Gene Information
human ... CYP1A2(1544)
Personal Protective Equipment
Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Hazard Codes
T
Risk Statements
45
Safety Statements
53-45
WGK Germany
3
RTECS
AB6825000
品名
產(chǎn)地
貨號
規(guī)格
單價
備注
氯霉素 Chloramphenicol
Sigma
C0378
5g
詢價
現(xiàn)貨
滬公網(wǎng)安備 31011002002623號
