LY 294002,LY294002,LY-294002
如果您對該產(chǎn)品感興趣的話,可以
產(chǎn)品名稱: LY 294002,LY294002,LY-294002
產(chǎn)品型號: Merck 440202-5MG
產(chǎn)品展商: 其他品牌
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
LY 294002,LY294002,LY-294002
LY 294002,LY294002,LY-294002
的詳細介紹
LY 294002,LY294002,LY-294002
LY 294002
MERCK相關(guān)產(chǎn)品資料：
440202 LY 294002 ( LY 294002 )
2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one
A cell-permeable, potent, reversible and specific phosphatidylinositol 3-kinase inhibitor (IC50 = 1.4 µM) that acts on the ATP-binding site of the enzyme. Also inhibits nonhomologous DNA end-joining (NHEJ) activity of the 460 kDa phosphatidylinositol 3-like kinase DNA-PKcs, which is the catalytic subunit of DNA-activated protein kinase. Does not affect the activities of EGF receptor kinase, MAP kinase, PKC, Pl 4-kinase, S6 kinase, and c-Src even at 50 µM. Blocks the proliferation of cultured rabbit aortic smooth muscle cells without inducing apoptosis. A 10 mM (1 mg/325 µl) solution of LY 294002 (Cat. No. 440204) in DMSO is also available.
|
Product number
|
型號
|
價格
|
|
440202-5MG
|
5 mg
|
詢價
|
|
產(chǎn)品信息
|
|
Form
|
Off-white solid
|
|
Primary Target
|
specific phosphatidylinositol 3-kinase inhibitor
|
|
Primary Target IC50
|
1.4 µM
|
|
Molar mass
|
307.4
|
|
Protect from Light
|
Yes
|
|
Cell permeable
|
Yes
|
|
Purity
|
≥98% by HPLC
|
|
Solubility
|
DMSO or EtOH
|
|
Chemical formula
|
C19H17NO3
|
|
CAS number
|
154447-36-6
|
|
Store and ship information
|
|
|
|
Storage
|
-20°C
|
|
Ship
|
Ambient Temperature Only
Standard Handling
|
